中文摘要：

目的：建立一种新的蔬菜、水果中多菌灵的超高效液相色谱-质谱/质谱测定方法。方法：多菌灵通过OasisHLB固相萃取柱分离浓缩后,采用超高效液相色谱-质谱/质谱仪的正离子模式电离和多反应离子检测模式进行测定,同时对诸如流动相的种类、色谱柱类型、锥孔电压和碰撞能量等参数进行了研究。结果：多菌灵在0.005～1.000mg/L范围内对响应值具有良好线性关系;样品的加标回收率为87.3%～105.6%,相对标准偏差小于15%（n=6）;方法检出限为1.0μg/L。结论：该方法测定特异性好、灵敏度高,定性定量准确,可用于实际样品测定。

英文摘要：

Aim：To establish a new analytical method for determination of carbendazim in vegetables and fruits by Ultra high-performance liquid chromatography-Tandem mass spectrometry（UPLC-MS/MS）.Methods：Carbendazim was isolated and concentrated by solid-phase extraction on Oasis HLB cartridges. The determination was carried out by UPLC-MS/MS in positive ionization and MRM modes. The influence of mobile phase composition,column types,corona current and fragmentor were also studied.Results：The response signals are linearly related with carbendazim concentrations in the range of 0.005～1.000 mg/L. The recoveries of carbendazim ranged from 87.3% to 105.6%,with the RSD15% （n=6）. The detection limit is 1.0 μg/L.Conclusion：The method presented can be used in real samples with highly selectivity,sensitivity and accuracy.