中文摘要：

采用循环伏安法和方波溶出伏安法研究了对乙酰氨基酚（ACOP）在玻碳电极上的电化学行为,结果发现,在pH=6.86的生理介质中,ACOP在玻碳电极上于0.53 V左右产生一对准可逆的氧化还原峰,在2.0×10-6~3.0×10-4mol/L浓度范围内与方波阳极溶出伏安峰电流有良好的线性关系,r=0.995 4,检出限为1.0×10-6mol/L.对5.0×10-5mol/L的ACOP重复测定8次,相对标准偏差为2.4%,可用于药剂中ACOP含量的测定.

英文摘要：

The electrochemical behaviors of acetaminophen （ACOP） are studied at glassy carbon electrode by cyclic voltammetry（CV） and square wave stripping voltammetry （SWV） in NaCl solution（pH 6.86）. The results show that ACOP electrochemical behaviors exhibit a sensitive quasireversible redox and the reduction and oxidation peak potential（Epa ,Epc） are 0. 566 and 0. 500 V respectively. The SWV peak currents are in linear relationship with the ACOP concentrations in the range of 2.0×10^- 6-3.0×10^-4 mol/L（r=0. 995 4）. The detection limit of this method is 1. 0 ×10^-6 mol/L and RSD is 2. 4%. This method is successfully used for the determination of ACOP in medicament with satisfactory results.