两性离子聚合物是一类同时具有酸性和碱性基团的聚合物,在特定pH环境以两性离子的形式存在.两性离子聚合物以水化性能强、抗细菌黏附能力显著、可电荷翻转及易化学修饰等优异性能引起了人们的广泛关注.本文主要根据两性离子聚合物的结构进行分类,并对其在恶性肿瘤的早期诊断和治疗领域的研究进行了分析和总结,展望了两性离子聚合物的发展前景.
Zwitterionic polymer is a kind of polymer both with acidic and basic groups, which exists in the form of zwitterion. Zwitterionie polymers have attracted our widespread attention because of the excellent per- formance of themselves, such as high hydration ability, significant anti-bacterial adhesion ability, charge con- version, be easily modified and so on. In this review, the variety of zwitterionic polymers will be classified ac- cording to the structure. The early diagnosis and treatment of malignant tumors by zwitterionic polymers were analyzed and summarized in this paper. Finally, the development of zwitterionic polymers in future is prospected.