中文摘要：

目的探讨青岛和哈尔滨地区男性原发性痛风临床特点的差异。方法采用回顾性研究方法,收集同一时段在青岛大学医学院附属医院痛风病临床医学中心和哈尔滨医科大学附属第四医院内分泌科初次就诊的男性原发性痛风病人664例,其中青岛地区362例,哈尔滨地区302例,对比分析两地区痛风病人的临床特征和生化指标。结果与青岛地区相比,哈尔滨地区痛风病人血尿酸和肌酐水平明显增高,差异有统计学意义（t=6.75,t′=2.55,P〈0.05）。哈尔滨地区痛风病人肾结石、痛风石和糖尿病的检出率明显高于青岛地区,差异有统计学意义（χ2=5.90～40.86,P〈0.05）。结论青岛和哈尔滨两地男性原发性痛风的临床特点存在明显差异,哈尔滨地区男性痛风病人血尿酸控制欠佳,痛风相关并发症的检出率较高。

英文摘要：

Objective To compare the differences of clinical characteristics of primary gout between Qingdao and Harbin. Methods By employing retrospective studies, the clinical data of 664 male patients with primary gout--362 from the Affiliated Hospital of Qingdao University Medical College and 302 from the Fourth Affiliated Hospital of Harbin Medical university-- were collected at the same time period. The clinical features and biochemical indicators were compared and analyzed. Results Compared with the patients in Qingdao area, the blood uric acid and creatinine levels of patients in Harbin were much higher （t = 6.75,t= 2.55;P d0.05）, and the detection rate of kidney stones, gouty deposition, and diabetes was also higher （X2 = 5.90-- 40.86, P（0.05）. Conclusion The difference of clinical features in male patients with primary gout between Qingdao and Harbin is significant. The control of blood uric acid in patients in Harbin is not good enough, ant the detection rate of gout-related compli- cations increases.