中文摘要：

主要研究了基于单探测器的偏振光学相干层析技术（PS-OCT）,探索并验证其定性检测生物组织双折射性质的能力。论述了单探测器PS-OCT系统检测组织双折射性质的理论,并利用Monte Carlo方法模拟了双折射对Stokes矢量分布的影响。在此基础上,搭建了单探测器PS-OCT系统,系统的纵向分辨率可达10 μm。利用该系统对牛软骨组织进行成像实验,获得反映牛软骨双折射性质的组织图像。理论和实验结果均表明,基于单探测器的PS-OCT系统可以检测组织双折射性质的变化,能够应用于医学诊断组织病变。

英文摘要：

The single-detector polarization-sensitive optical coherence tomography （PS-OCT） is studied,aiming at validating its ability to detect qualitatively the birefringence of biological tissue. The theory of single-detector PS-OCT detecting the birefringence of biological tissue was described,and the influence of birefringence on the Stokes vector was demonstrated with Monte Carlo simulation. A single-detector PS-OCT system was set up,which has a theoretical resolution of 10 μm,and experiment was performed on a bovine cartilage sample. The PS-OCT image indicated the birefringence of cartilage. The theoretical analysis and experiments results prove the ability of single-detector PS-OCT detecting tissue birefringence and the possibility of using single-detector PS-OCT in medical diagnosing domain.