中文摘要：

目的：探讨降钙素原（PC T ）、中性粒细胞比率（N％）及D‐二聚体在高龄慢性阻塞性肺疾病急性加重期（AECOPD）患者中的诊断价值。方法收集不小于75岁的住院 AECOPD患者共128例，根据 PCT 水平分为PCT＜0．05 ng／mL组及PCT≥0．05 ng／mL组，入院后使用抗生素前检测其血清PCT、N％及D‐二聚体，分析其相关性。结果 PCT＜0．05 ng／mL组患者N％及D‐二聚体水平均低于PCT≥0．05 ng／mL组，差异均有统计学意义（ P＜0．05）；PC T与N％（ r＝0．789，P＝0．006）及D‐二聚体（ r＝0．695，P＝0．034））均呈正相关。结论高龄A E‐COPD患者 PCT 水平越高，其 N％、D‐二聚体水平也越高，三者之间具有一致性，故指标联合检测更有利于高龄AECOPD早期更准确的诊断。

英文摘要：

Objective To investigate the diagnostic value of procalcitonin （PCT） ,neutrophil ratio（N% ） and D‐dimer in elderly patients with acute exacerbation of chronic obstructive pulmonary disease （AECOPD） .Methods 128 inpatient with AECOPD aged no less than 75‐year‐old were collected and divided into the PCT 〈0 .05 ng/mL group and the PCT≥0 .05 ng/mL group according to the PCT levels .Serum PCT ,N% and D‐dimer were detected before antibiotic use .Then the relevance was analyzed .Results N% and D‐dimer level in the PCT 〈 0 .05 ng/mL group were lower than those in the PCT ≥0 .05 ng/mL group with statistical differences between 2 groups ;PCT showed the positive correlation with N% （r=0 .789 ,P=0 .006） and D‐dimer（r=0 .695 ,P=0 .034） respectively .Conclusion The higher the PCT level ,the higher the N% and the D‐dimer level in elderly patients with AECOPD ,which show‐ing the consistency among the three ,therefore the combined detection of 3 markers is more conducive to a more accu‐rate diagnosis of early AECOPD .