中文摘要：

目的了解青海省三江源地区人群棘球蚴病流行现状，为控制棘球蚴病的流行提供依据。方法对三江源地区6个州的11个县（市）1岁以上常住人口进行现场流行病学调查，采用间接红细胞凝集试验（IHA）检测人群血清中抗棘球蚴IgG抗体，确定感染率。结果共检查人血清8408份，检出抗棘球蚴IgG抗体阳性者862例，总阳性率为10．25％。其中女性阳性率为12．79％（532／4161），男性阳性率为7．77％（330／4247），女性高于男性（X^2=57．45，P〈0．01）；棘球蚴病感染率在各年龄组间比较差异有统计学意义（X^2=146．30，P〈0．01）．其中50岁年龄组[16．77％（105／626）]和≥60岁年龄组[16．00％（52／325）]高于其他年龄组；感染率在各职业人群间分布比较差异有统计学意义（X^2=188．02，P〈0．01），其中僧侣[25．60％（31／117）]高于其他职业人群；感染率存各民族间比较差异有统计学意义（X^2=93．42，P〈0．01），其中蒙古族、藏族[11．35％（786／6927）、17．43％（38／218）]明显高于其他民族；感染率地区分布比较差异有统计学意义（X^2=2572．33，P〈0．011，较高的县依次为南部的久治县[25．97％（287／1113）]、称多县[25．48％（132／518）]、泽库县[16．44％（172／1046）]和河南县[12．84％（52／405）]。结论棘球蚴病在三江源地区均有分布，感染率以南部牧区为主。防治工作重点应针对广大牧区，以牧区的女性、蒙古族、藏族、僧侣、农牧民为主要目标人群。

英文摘要：

Objective To explore the current prevalence of human echinococcosis and to lay foundations for establishing preventive and control strategies in Three-River Source area of Qinghai. Methods Local habitants aged more than 1 year old were selected for survey. Their antiechinococcosis IgG in serum was determined by indirect hemagglutination （IHA） to detect human echinococcosis in 11 counties of 6 states in Three-River Source area. Results A total 8408 people examined, 862 were found to be positive, the positive rate being 10.25%. The seropositive rates were 12.79%（532/4161） and 7.77%（330/4247） in female and male, respectively. The positive rate in female was significantly higher than that in male（x^2 = 57.45, P 〈 0.05）. The difference was statistically significant （X^2 = 146.30, P 〈 0.05） in different age groups. The positive rates in the group aged 50 or more than 60 years old [ 16.77%（105/626）, 16.00% （52/325）J were higher than those in other age groups. The difference was statistically significant （X^2 = 188.02, P 〈 0.05） in different occupation groups. Monk ＇ s infection rate [25.60% （31/117） ] was higher than other professions. Statistically, infection rates were significantly different （X^2 = 93.42, P 〈 0.05） in different nationality groups. The rate was 17.43%（38/218） in Mongolian and 11.35%（786/6927） in Tibetan, being obviously higher than that in other nationalities. The infection rates were statistically different （X^2 = 2572.33, P 〈 0.05） in different county groups. The positive rates in the groups from Jiuzhi [25.97%（287/1113）], Chengduo [ 25.48% （ 132/518 ） ], Zeku [ 16.44% （ 172/1046 ） ] and Henan [ 12.84% （52/405） ] counties in south were higher. Conclusions Echinococcosis is found in all surveyed areas, especially serious in pastoral area. It is suggested that a comprehensive control program should be made to prevent and control the disease in the area.