中文摘要：

目的观察干扰HSPC238对宫颈癌Hela细胞裸鼠成瘤的影响。方法将PLL3.7-HSPC238干扰载体稳定转染Hela细胞,然后将细胞接种到BALB/c裸鼠前肢腋部皮下,观察肿瘤出现时间及体积变化。结果转染了PLL3.7-HSPC238干扰载体组的裸鼠肿瘤较对照组生长快,肿瘤的体积明显大于对照组,差异有统计学意义（P〈0.05）。结论干扰HSPC238对宫颈癌Hela细胞裸鼠成瘤具有促进作用。

英文摘要：

Objective To investigate the effect of interfering HSPC238 on cervical cancer Hela cells tumorigenesis in nude mice.Methods PLL3.7-PSMA7 interfering vectors were stably transfected into Hela cells.Then the cells were subcutaneously inoculated into the anterior limb armpit of the BALB/c nude mice.The appearance time and volume change of tumor were observed.Results Compared with control group,the nude mice tumor of the transfected PLL3.7-HSPC238 interfering vector group grew more fast and the volume was bigger,the difference was statistically significant.Conclusion Interfering HSPC238 has a promoting effect on cervical cancer Hela cell tumorigenesis in nude mice.