用模型化合物来模拟DNA光解酶与底物的作用,有助于认识DNA光复活作用机理.评述了环丁烷型嘧啶二聚体光解酶和(6-4)光产物光解酶的模型研究进展,并展望了该领域的发展前景.
The information for the mechanism of DNA photolyase can be obtained by using model compounds to mimic the repair process of DNA photoreactivation. In this paper, recent progresses in model studies of cyclobutane pyrimidine dimer photolyases and (6-4)photoproduct photolyases have been reviewed.