中文摘要：

去辅基的DNA光解酶在280nm光辐照下，能高效修复底物嘧啶二聚体（Ф=0．56）．为了模拟酶蛋白的这一修复过程，合成了色氨酸（Trp）和／或酪氨酸（Tyr）与胸腺嘧啶二聚体（D）共价连接的化合物，作为酶-底物复合物的模型，研究了它们在295nm光照射下氨基酸残基光敏化二聚体裂解的性质，测定了二聚体裂解量子产率（Ф），获得一些新的结果并对其进行了分析．

英文摘要：

The apoenzyme ofDNA photolyase can efficiently repair its substrate after excitation by 280 nm light （Ф=0.56）. In order to mimic this repair process of apoenzyme, we synthesized two model compounds, in which tryptophan and/or tyrosine was covalently linked to cyclobutane thymine dimer, and measured the splitting quantum yield of dimer under 295 nm light. By investigating the photosensitized splitting properties of the dimer, some new insights into the intramolecular electron-transfer process were gained.