中文摘要：

EDR2 在 Arabidopsis 是防卫反应和房间死亡的一个否定管理者。EDR2 的 Loss-of-function 导致提高的抵抗到粉的霉。为了在 EDR2 识别新部件，表明 transduction 小径，压制 edr2 的变化抵抗显型被屏蔽。三异种， edts5-1， edts5-2 和 edts5-3 (edr 二 suppressor 5 ) ，被识别。EDTS5 基因被基于地图的克隆识别并且以前被显示编码 aminotransferase (ALD1 ) 。因此，我们分别地重命名这三等位基因 ald1-10， ald1-11 和 ald1-12。在 ALD1 的变化压制了所有调停 edr2 的显型，包括粉的霉抵抗，规划房间死亡和导致乙烯的老朽。在 edr2 的氢过氧化物的累积被 ald1 变化也压制。防卫相关的基因的表示在 edr2 异种是起来调整的，并且在 edr2 的那些基因的起来规定在 edr2/ald1 被压制两倍异种。ald1 单身者异种显示了推迟的导致乙烯的老朽。另外， ald1 变化压制了调停 edr1 的粉的霉抵抗，但是不能压制 edr1/edr2 双异种显型。这些数据证明 ALD1 在调停 edr2 的防卫回答，和老朽起重要作用并且表明在发信号的乙烯和水杨酸酸之间的串音由 ALD1 和 EDR2 调停了。

英文摘要：

EDR2 is a negative regulator of the defense response and cell death in Arabidopsis.Loss-of-function of EDR2 leads to enhanced resistance to powdery mildew.To identify new components in the EDR2 signal transduction pathway,mutations that suppress edr2 resistant phenotypes were screened.Three mutants,edts5-1,edts5-2 and edts5-3（edr two suppressor 5）,were identified.The EDTS5 gene was identified by map-based cloning and previously was shown to encode an aminotransferase（ALD1）.Therefore we renamed these three alleles ald1-10,ald1-11 and ald1-12,respectively.Mutations in ALD1 suppressed all edr2-mediated phenotypes,including powdery mildew resistance,programmed cell death and ethylene-induced senescence.Accumulation of hydrogen peroxide in edr2 was also suppressed by ald1 mutation.The expression of defense-related genes was up-regulated in the edr2 mutant,and the up-regulation of those genes in edr2 was suppressed in the edr2/ald1 double mutant.The ald1 single mutant displayed delayed ethylene-induced senescence.In addition,ald1 mutation suppressed edr1-mediated powdery mildew resistance,but could not suppress the edr11edr2 double-mutant phenotype.These data demonstrate that ALD1 plays important roles in edr2-mediated defense responses and senescence,and revealed a crosstalk between ethylene and salicylic acid signaling mediated by ALD1 and EDR2.