目的:研究毛杜仲藤皮的化学成分。方法:用硅胶,制备薄层层析等手段进行分离纯化,根据化合物的理化性质和光谱数据鉴定结构。结果:分离并鉴定了9个化合物,即大黄素甲醚(1),延胡索酸(2),龙胆酸甲酯(3),丁香酸甲酯(4),丁香酸(5),2,5-二甲氧基对苯醌(6),香草酸(7),3,4,5-三甲氧基苯甲酸(8),6-甲氧基-7-羟基香豆素(9)。结论:所有化合物均首次从该植物中分离得到。
AIM: To investigate the chemical constituents of Parabarium huaitingii. METHODS: The constituents were isolated and purified by silica gel column chromatography and preparative TLC. Their structures were identified on the basis of spectral data and physiochemical properties. RESULTS: Nine compounds were isolated and their structures were elucidated as physcion (1), fumaric acid (2), methyl gentisate (3), 4-hydroxy-3, 5-dimethoxybenzoic acid methyl ester (4), syringic acid (5), 2, 5-dimethoxy-pbenzoquinone (6), vanillic acid (7), 3, 4, 5-trimethoxybenzoic acid (8) and 6-methoxy-7-hydroxycoumarin (9). CONCLUSION: All of the compounds were isolated from this genus for the first time.