当今医学模式正在由疾病医学向健康医学转化,由此提出了强调个体化、预测性、预防性和参与性的4P医学模式。痰湿体质是中国人9种体质类型之一,也是研究最多的体质类型。对痰湿体质的基因组学和单核苷酸多态性研究体现了体质的个体差异性;痰湿体质与疾病的相关性研究表明痰湿体质者有患代谢综合征、高血压病、2型糖尿病等疾病的发病倾向,使用《中医体质量表》在人群中进行痰湿体质的判定,估计以上疾病发生的风险,体现了对疾病的预测性;通过干预痰湿体质,减少肥胖相关疾病的发生风险,体现了预防性。体质辨识应用于临床和公共卫生服务,在辨识过程中充分强调服务对象的参与性。因此,中医痰湿体质研究体现了4P医学模式的实践和运用,为其他学科在当今医学模式下的研究和发展提供了范式。
The aim of modern medicine is transforming from disease to health.Thus the medical model of 4P was proposed in recent years.4P include preventive,predictive,personalized and participatory.Phlegm-dampness constitution was one of the nine constitutions and much more research were done on it than on the other constitutions.The study on genomics and single nucleotide polymorphisms(SNPs) on phlegm-dampness constitution showed the individual difference of constitution of people.The correlation between phlegm-dampness constitution and metabolic syndrome,hypertension and diabetes type 2 showed the potential tendency of phlegm-dampness constitution to these diseases.So constitution differentiation can be used to predict the happening risk of disease by using the assessment scale of constitution.Prevention and treatment of obesity and the correlated disease could be done through regulating of phlegm-dampness constitution.And during the course of constitution differentiation,the object of service or patients can participate in the whole course.In the summary,the research of phlegm-dampness constitution embodies the implementation of 4P medical model.And it provided the pattern of research and development for other subjects.