中文摘要：

电子顺磁的回声成像(EPRI ) 是一种相对最近的成像技术，它提供顺磁的种类的空间分发的潜在地多维的成像。由于稳定的旋转探针的使用，低频率 EPR 成像最近在生物学和药的领域里在 vivo 允许大组织样品或整个动物的使用。介绍马厩或慢慢地的优先的静脉内或肌内的注入是通常必要的 metabolizable 无毒的水溶性的顺磁的材料，或马厩作为旋转探针植入有能力的微粒材料进系统。旋转探针的分类和研究进步目前简短被描述。在水溶性的顺磁的材料的三条重要潜在的途径设计包括 deuterated，地点特定并且宏分子的结合的 nitroxides 也被调查。

英文摘要：

Electron paramagnetic resonance imaging （EPRI） is a relatively recent imaging technique, which provides potentially multidimensional imaging of the spatial distribution of paramagnetic species. Thanks to the use of stable spin probes, low frequency EPR imaging has recently allowed the use of large tissue samples or whole animals in vivo in the field of biology and medicine. It is normally necessary to introduce prior intravenous or intramuscular infusion of stable or slowly metabolizable non-toxic water-soluble paramagnetic materials, or stable implantable particulate materials as spin probes into the system. The classification and research progress of spin probes at present were described briefly. Three important potential approaches in water-soluble paramagnetic materials design including deuterated, site-specific and macromolecular conjugated nitroxides were also investigated.