中文摘要：

目的影响子宫内膜癌预后的因素很多,目前这些因素对子宫内膜癌预后的影响,并没有得到一致的认同。因此,我们进一步分析了影响子宫内膜癌预后的相关因素。方法回顾性地分析了中国医科大学第一附属医院妇科.2004年8月到2014年8月共361例子宫内膜癌患者,采用卡方检验进行子宫内膜癌预后因素的单因素分析,并采用COX回归模型对其进行多因素分析。结果单因素分析表明,年龄、雌激素受体、孕激素受体、肌层浸润深度、FIGO（2009）分期、组织学类型、病理分级、宫颈转移、输卵管卵巢转移、淋巴结转移、淋巴血管间隙浸润（LVSI）影响子宫内膜癌的预后（P〈0.05）,而身高体重指数（BMI）、发病时绝经情况、糖尿病、高血压,与子宫内膜癌的预后无关（P〉0.05）。COX回归分析表明,肌层浸润深度、FIGO（2009）分期、病理分级、淋巴血管间隙浸润为子宫内膜癌独立的预后因素。结论对具有独立预后影响因素的子宫内膜癌患者,在接受手术的同时,应采取积极的放化疗。

英文摘要：

Objective There are many factors affecting the prognosis of endometrial carcinoma,but with no consistent agreement about the prognosis factors.Therefore,we further analyzed the related factors influencing the prognosis of endometrial carcinoma.Methods We retrospectively analyzed 361 cases of patients with endometrial carcinoma in gynecology department of the first affiliated hospital of China Medical University from August 2004 to August 2014.We used a two-tailed Chi-square test to product univariate analysis,and indentified the clinical pathologic features related to the prognosis of endometrial carcinoma.In addition,we used multivariable COX regression to identify the independent prognosis factors.Results Univariate analysis showed that the factors of age,estrogen receptor,progesterone receptor,FIGO（2009）stage,histological type,pathological grade,cervical metastasis,the tubal and ovarian metastasis,lymph node metastasis and lymph vascular space invasion were significant prognosis factors＇ of endometrial carcinoma（P〈0.05）;but the height and body weight index（BMI）,menopausal status,diabetes and hypertension were not the prognosis factors for endometrial carcinoma（P〈0.05）.COX- regression analysis indicated that the depth of muscle invasion,FIGO（2009） stage,pathological grade,and lymph vascular space invasion were the independent prognostic factors（P〈0.05）.Conclusion The aggressive radiotherapy and chemotherapy should be applied for the patients of endometrial carcinoma with independent prognosis factors after operation.