中文摘要：

在这个工作，我们开发了一个高度敏感的方法基于颠倒的阶段液相色层分析法质谱分析法检测三聚氰胺。质谱分析法兼容机离子对， heptafluorobutyric 酸(HFBA ) ，被用来在电镀物品以前由颠倒的阶段液相色层分析法分开三聚氰胺祈祷质谱分析法。同位素的加入监视的内部标准、多重的反应改进了数量化的精确性和线性离子。基于这策略，数量化离子的方法限制是 0.1 ng/g。数量化离子的限制为干燥奶粉是为液体牛奶和 15 ng/g 的 8 ng/g。这个方法提供了一条可再现、稳定的途径给敏感察觉和三聚氰胺的数量化离子。

英文摘要：

In this work, we developed a highly sensitive method to detect melamine based on reversed phase liquid chromatography mass spectrometry. A mass spectrometry compatible ion pair, heptafluorobutyric acid（HFBA）, was used to separate melamine by reversed phase liquid chromatography prior to electrospray mass spectrometry. The incorporation of isotope internal standard and multiple reaction monitoring improved the accuracy and linearity of quantification. Based on this strategy, the method limit of quantification was 0.1 ng/g. The limits of quantification were 8 ng/g for liquid milk and 15 ng/g for dry milk powder. This method provided a reproducible and stable approach to sensitive detection and quantification of melamine.