基础 ganglia 被侵略 electrophysiolgic 在自发的概括癫痫(IGE ) 在一个调整角色含有工具。这份报纸调查基础 ganglia 由在休息状态使用区域明智的功能的连接分析的功能的连接在 IGE 的功能的磁性的回声成像(fMRI ) 。在基础 ganglia 以内的增加的功能的连接,并且在基础 ganglia 和丘脑之间,并且在基础 ganglia 之间的减少的功能的连接和马达外皮与控制相比在 IGE 被发现。这些调查结果不仅含有在马达的不正常的集成在调制循环在 IGE 和提高的相互作用循环,而且建议基础 ganglia 在 corticothalamus 网络在丘脑上与影响调制概括癫痫的分泌物。
The basal ganglia have been implicated in a modulation role in idiopathic generalized epilepsy (IGE) by an invasive electrophysioigic means. This paper investigates the basal ganglia functional connectivity by using the region-wise functional connection analysis in resting-state functional magnetic resonance imaging (fMRI) in IGE. The increased functional connectivity within basal ganglia, and between the basal ganglia and the thalamus, and decreased functional connectivity between basal ganglia and motor cortex are found in IGE compared with the controls. These findings not only implicate dysfunctional integration in the motor loop in IGE and the enhanced interaction in the modulated loop, but also suggest that the basal ganglia modulate the generalized epileptic discharges with the influence over thalamus in the corticothalamus network.