中文摘要：

利用新型催化剂固体超强酸SO4 2-／TiO2催化合成了维生素E油酸酯，研究了油酸酰氯与维生素E摩尔比（X1）、反应温度（X2）、催化剂用量（X3）、反应时间（X4）对维生素E油酸酯产率的影响，以单因素实验为基础，利用响应面法优化了工艺条件。结果表明：SO4 2-／TiO2催化合成维生素E油酸酯较优工艺条件为油酸酰氯与维生素E摩尔比3：1，反应温度50℃，SO4 2-／TiO2用量5．5％，反应时间4h；在较优工艺条件下，维生素E油酸酯产率达到92．2％。

英文摘要：

Vitamin E oleate was synthesized with novel catalyst solid super acid SO4 2-/TiO2. The effects of molar ratio of oleic acid chloride to vitamin E （X1 ）, reaction temperature （ X2 ）, dosage of SO4 2 -/TiO2 （X3 ） and reaction time（X4 ） on yield of vitamin E oleate were researched, and the conditions were optimized by response surface methodology based on single factor experiment. The results showed that the optimal synthesis conditions of vitamin E oleate catalyzed by SO4 2-/TiO2 were obtained as follows： molar ratio of oleic acid chloride to vitamin E 3： 1, reaction temperature 50 ℃, dosage of SO4 2-/TiO2 5.5% and reaction time 4 h. Under the optimal conditions, the yield of vitamin E oleate reached 92.2%.