阿尔茨海默病是痴呆最常见的类型。近年来研究表明Tau蛋白异常过度磷酸化与AD的发病有关。本文从Tau蛋白病因假说角度对AD的发病机制、诊断和治疗作一综述。
Alzheimer' s disease is the most common cause of dementia, and recent researches indicate that Alzheimer' s disease is relevant with Tau hyperphosphorylation, so this article reviews the advances in researches on the pathogenesis, diagnosis and treatment of Alzheimer' s disease from the perspective of Tau hypothesis.