提出了一种结构简单、可编程控制的离散液滴控制芯片。它以硅为衬底,重掺杂多晶硅为微电极阵列,氧化硅为介质层,碳氟聚合物薄膜为疏水层。它克服了传统连续流传输、混合的局限性及层流条件的限制,通过控制施加在微电极阵列上的电压脉冲时序,成功实现了对离散液滴的快速传输和混合。在30V驱动电压下,约0.9μL去离子水液滴传输速度可达24mm/s;在40V驱动电压下,约0.8μL去离子水液滴和约1.4μL的0.0001mol/L Rhodamine液滴在7/30s内完成了快速混合。另外,还提出利用提高液滴速度及来回晃动混合后的液滴等几种加强混合方法。
A prototype of a programmable electrostatic-based liquid droplet controlling chip with a simple configuration is presented, consisting of Si used as the substrate, heavy doped poly-silicon as the microelectrode array, a SiO2 film as the dielectric layer and a fluorocarbon polymer film as the hydrophobic layer. It overcomes the shortcomings of the traditional continuous flow system and the limitation of laminar flow conditions. By controlling the sequence of voltage pulses applied to the microelectrode array under the dielectric layer, droplets on the surface of the hydrophobic layer can be quickly transported and mixed. The rapid transportation of the deionized droplet with about 0.9 μL was successfully achieved in air by applying the voltage pulse of 30 V, and the transportation speed reached 24 mrn/s. The quick mixing between the deionized droplet with about 0.8 μL and the 0. 0001 mol/L rhodamine droplet with about 1.4 μL was successfully carried out in 7/30 s by applying the voltage pulse of 40 V, and the several methods for enhancement mixing were researched, including increasing the transportation speed of the droplets and enhancing the oscillation of the mixed droplet.