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中文摘要：
生物传感器的研制越来越趋向于微型化、集成化、智能化以及无创伤的方向发展．研制基于微／纳米加工技术的电化学免疫传感器顺应了这一趋势，利用微电子机械系统（MEMS）技术在硅基芯片上制备微型三电极系统和SU-8微型池，并采用自组装单层膜和纳米金修饰微型电极表面用于抗体的固定化，研制出新型的电化学免疫传感器．研究表明，这种微型电化学免疫传感器易于实现批量生产，便于集成，检测过程只需要少量的样品，大大降低有毒试剂的消耗，减少环境污染，同时具有分析成本低，响应时间快，检测下限低和适用于现场快速检测等优点．
英文摘要：
The research and development of biosensor is marching toward miniaturization, integration, intelligence and non-invasion. Study on the electrochemical immunosensor based on micro/nano fabrication technology is of great significance in practical application. A novel immunosensor has been developed by employing MEMS technology, self-assembled monolayers （SAMs） and gold nanoparticles （nanogold） for the preparation of micro electrode system and the immobilization of antibody. This kind of miniature sensors allows for low-cost production in batch processes and compatibility with CMOS technology, needs only a small amount of sample solution, reduces the consumption of toxic reagents, decreases the environmental pollution, enables relatively rapid, reliable and inexpensive field-analysis.
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