中文摘要：

动脉粥样硬化是一种严重危害人类健康的疾病。氧化应激、血管病变、炎症反应在动脉粥样硬化发生中起关键作用。近年来研究发现，氧化应激是动脉粥样硬化斑块形成中的重要因素。血管系统中内源性气体信号分子NO、Co、H2S作为一种独特的血管活性物质，分别与其相应的合成酶一氧化氮合酶（NOS）、血红素加氧酶（HO）和胱硫醚-r-裂解酶（CES）形成独立而又相互关联的体内重要抗氧化系统，可以减少动脉粥样硬化的严重度。运动可以造成氧化应激，但有规律有计划的体育运动可以通过基因水平上调节氧化还原信号增强机体抗氧化能力。最近研究发现，运动能诱导气体信号分子相应的合成酶合成，对动脉粥样硬化病理形成和发展具有阻抑作用。

英文摘要：

Arthrosclerosis （AS） is one kind of severely imparing health disease. The oxidized stress, the blood vessel pathologieal change and the inflammation responded all play a role in atherosclerosis. The recent researches show that the oxidized stress is an important factor in AS formation. In the car- diovascular system, the endogenous NO, CO, and H2S form three specific and relevant pathways with their corresponding enzymes including nitric oxide syntheses （NOS）, the home oxygenize （H0） and cystathionine r-lyric enzyme （CES）, whose affect can relieve the atherosclerosis. Sports can lead to oxidized stress, but regular and scientific sports can enhance organism oxidation resistance ability through genetic level. Sports can induce the gas signal member corresponding enzyme synthesis, in- hibiting the formation of atherosclerosis.