中文摘要：

我们研究了具有镇痛活性的螺环哌嗪季铵盐二溴代物1a—1e的一级和二级质谱。化合物1脱去溴负离子生成[M．Br]^＋峰2，离子2脱去溴化氢分子形成离子峰4，离子[M-Br-44]^＋3N基峰。化合物1d—1e由于是酰胺类化合物，除了上述几类峰外，还生成了离子碎片[M-2Br-33]^＋。

英文摘要：

The fragmentation patterns of a series of dispirocyclopiperazinium dibromides with strong analgesic activity during positive ion electrospray ionization mass spectrometry were analyzed. The [M-Br]^＋ 2 ions showed the characteristic isotopic peaks and were assigned as the molecular ions. The loss of a 44 Dalton unit from 2 produced ion 3 [M-Br-44]^＋ and the loss of HBr from 2 formed ion 4. Besides, the carbamates 1d-1e produced extra ions [M-2Br-33]^＋. The related fragmentation mechanisms were proposed.