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Efficacy and significance of various scores for pneumonia severity in the management of patients with community-acquired pneumonia in China
  • ISSN号:0366-6999
  • 期刊名称:《中华医学杂志:英文版》
  • 时间:0
  • 分类:S858.28[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医] X823[环境科学与工程—环境工程]
  • 作者机构:[1]Zhejiang Univ, Affiliated Hosp 2, Dept Resp Med, Sch Med, Hangzhou 310009, Zhejiang, Peoples R China, [2]Zhejiang Univ, Affiliated Hosp 2, Dept Intens Care Unit, Sch Med, Hangzhou 310009, Zhejiang, Peoples R China, [3]Zhejiang Univ, Affiliated Hosp 2, Dept Infect Prevent & Control, Sch Med, Hangzhou 310009, Zhejiang, Peoples R China, [4]Hangzhou Normal Univ, Div Immunol, Hangzhou 310036, Zhejiang, Peoples R China, [5]Zhejiang Univ, Affiliated Hosp 2, Dept Internal Med, Binjiang Branch,Sch Med, Hangzhou 310009, Zhejiang, Peoples R China, [6]Hangzhou Binjiang Hosp, Hangzhou 310009, Zhejiang, Peoples R China
  • 相关基金:This study was supported by grants from the National Natural Science Foundation of China (No.30871130 and 30500229),the Qianjiang Talent Project of Science and Technology Department of Zhejiang Province (No.2010R10080),and the Youth Talent Fund of Health Bureau of Zhejiang Province,China (No.2008QN016).
中文摘要:

背景获得社区的肺病(帽子)在 world.Most 附近从传染疾病仍然是领先的原因 ot 死亡之一严重帽子病人进入特别护理单位( ICU ),并且收到学习试图评估肺病严厉索引(希腊语的第二十三个字母)的角色的在场的强烈 treatment.The , CURB-65 ,并且败血在就医的帽子病人的管理得分并且在 675 个帽子病人的一个总数就医了在的严重 cases.Methods 的预后上探索 ICU 治疗的效果

英文摘要:

Background Community-acquired pneumonia (CAP) remains one of the leading causes ot death from infectious diseases around the world.Most severe CAP patients are admitted to the intensive care unit (ICU),and receive intense treatment.The present study aimed to evaluate the role of the pneumonia severity index (PSI),CURB-65,and sepsis score in the management of hospitalized CAP patients and explore the effect of ICU treatment on prognosis of severe cases.Methods A total of 675 CAP patients hospitalized in the Second Affiliated Hospital of Zhejiang University School of Medicine were retrospectively investigated.The ability of different pneumonia severity scores to predict mortality was compared for effectiveness,while the risk factors associated with 30-day mortality rates and hospital length of stay (LOS) were evaluated.The effect of ICU treatment on the outcomes of severe CAP patients was also investigated.Results All three scoring systems revealed that the mortality associated with the low-risk or intermediate-risk group was significantly lower than with the high-risk group.As the risk level increased,the frequency of ICU admission rose in tandem and LOS in the hospital was prolonged.The areas under the receiver operating characteristic curve in the prediction of mortality were 0.94,0.91 and 0.89 for the PSI,CURB-65 and sepsis score,respectively.Compared with the corresponding control groups,the mortality was markedly increased in patients with a history of smoking,prior admission to ICU,respiratory failure,or co-morbidity of heart disease.The differences were also identified in LOS between control groups and patients with ICU treatment,heart,or cerebrovascular disease.Logistic regression analysis showed that age over 65 years,a history of smoking,and respiratory failure were closely related to mortality in the overall CAP cohort,whereas age,ICU admission,respiratory failure,and LOS at home between disease attack and hospital admission were identified as independent risk factors for mortality in th

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期刊信息
  • 《中华医学杂志:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京东四西大街四十二号
  • 邮编:100710
  • 邮箱:cmj@cma.org.cn
  • 电话:010-85158321
  • 国际标准刊号:ISSN:0366-6999
  • 国内统一刊号:ISSN:11-2154/R
  • 邮发代号:2-920
  • 获奖情况:
  • 1997、1998、1999年获中国科协优秀科技期刊择优资...,1992、1997年连续两年荣获全国优秀科技期刊和中国...,中国期刊方阵双高期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国科学引文索引(扩展库),美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊
  • 被引量:3319