中文摘要：

目的研究C群流行性脑脊髓膜炎病例年龄分布特征。方法通过疾病监测系统收集合肥地区流行性脑脊髓膜炎病例资料。结果研究期间共发现收集386例C群流行性脑脊髓膜炎病例,病例年龄中位数为15岁（2个月龄-78岁）,年龄别发病率最高的为6.57/10万（12-17岁）,该年龄段病例占总病例的31.35%;病死率最高的年龄段为0-5岁,病死率为16.90%。结论随C群流行性脑脊髓膜炎发病率上升,病例年龄分布呈现从小年龄组向青少年和年轻成人组转变趋势,但这可能是疫情流行期间暂时的特征。

英文摘要：

Objective To determine the shift of the age distribution of meningococcal disease caused by serogroup C. Methods Data about each patient with meningococcal disease were collected from the National Disease Surveillance System. Results During study period, 386 cases with meningococcal disease caused by serogroup C were reported. The median age of these patients was 15 years （ranged from 2 months to 78 years）. Analysis by age group, the highest age-specific incidence rate （6.57 per 100 000 population） and the highest proportion （31.35 % ） of cases occurred in age 12 - 17. The peak case-fatality rate （CFR） of 16.90 % was found in small children （aged 0--5 years old）. Conclusions A shift to adolescents and young adults has been found in the age distribution of cases, along with the increasing in the incidence of meningococcal disease caused by serogroup C. But it may be a sign of epidemic.