Structure-based protein-protein interaction networks and drug design
- 分类:Q811.4[生物学—生物工程] TQ460.1[化学工程—制药化工]
- 作者机构:[1]Chinese Academy of Sciences Key Laboratory of Computational Biology, Chinese Academy of Sciences-Max Planck PartnerInstitute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai200031, China
- 相关基金:This work was funded by grants from the National Natural Science Foundation of China (NSFC) (Grant No. 31210103916 and 91019019), Chinese Ministry of Science and Technology (Grant No. 2011CB504206) and Chinese Academy of Sciences (CAS) (Grant Nos. KSCX2-EW-R-02 and KSCX2-EW-J-15) and stem cell leading project XDA01010303 to J.D.J.H.H.N. was supported by the Chinese Academy of Sciences Fellow- ship for Young International Scientist [Grant No. 2012Y1SB0006] and the National Natural Science Foundation of China [Grant No. 31250110524]. The authors thank Dr. Jerome Boyd-Kirkup for extensive editing and Hamna Anwar for proofreading the manu- script.
关键词:
蛋白质相互作用网络, 药物设计, 结构, 蛋白相互作用, 分子相互作用, 药物开发, 有用性, 图论, protein-protein interaction, network, structure-based, drug design, drug reposition
中文摘要:
Correspondence: jdhan@picb.ac.cn