中文摘要：

连作障碍的研究虽然已经有多年的历史,但目前仍没有有效的治疗方法,其根本原因是其形成体系的复杂性。该文从连作植物根际土壤多元因子的互作关系入手,详细阐述了栽培植物连作障碍形成的生理生态机制,提出了栽培药用植物、自毒化感物质和根际微生物间复杂的多元互作是驱动连作障碍形成的根本原因,指出了植物功能基因组学和代谢组学以及微生物宏组学相结合的多元组学技术在深入理解特定生境多因子互作关系研究中的优势。同时,该文以地黄为例,从根际化感自毒物质累积效应、根际微生态的灾变及连作植株的分子响应等多元角度综述了地黄连作障碍形成的分子机制,并详细总结了多元组学技术在这些机制研究中的运用和进展。该文为从分子水平上系统地揭示栽培药用植物连作障碍形成的分子机制提供了新的思路。

英文摘要：

Although consecutive monoculture problems have been studied for many years,no effective treatments are currently available. The complexity of systems triggered the formation of consecutive monoculture problems was one major cause. This paper elaborated the physiological and ecological mechanisms of consecutive monoculture problem formation based on the interaction relationship among multiple factors presented in the rhizosphere soil of consecutive monoculture plants. At same time,in this paper the multiple interactions among cultivated medicinal plants,autotoxic allelochemicals and rhizosphere microbial were proposed to be most important causes that derived the formation of consecutive monoculture problem. The paper also highlighted the advantage of ＇omics＇ technologies integrating plant functional genomics and metabolomics as well as microbial macro-omics in understanding the multiple factor interaction under a particular ecological environment. Additionally,taking R. glutinosa as an example,the paper reviewed the molecular mechanism for the formation of R. glutinosa consecutive monoculture problem from the perspective of the accumulation of allelopathic autotoxins,the rhizosphere microecology catastrophe and theresponding of consecutive monoculture plants. Simultaneously,the roles of mutilple ＇omics＇ technologies in comprehending these formation mechanism were described in detail. This paper provides finally a new insight to solve systematically the mechanism of consecutive monoculture problem formation on molecular level.