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治疗前列腺增生药物作用特点分析
  • ISSN号:1672-6839
  • 期刊名称:中医学报
  • 时间:2014.1.1
  • 页码:61-63
  • 分类:R286[医药卫生—中药学;医药卫生—中医学]
  • 作者机构:[1]河南中医学院,河南郑州450008
  • 相关基金:国家自然科学基金(编号:81173474); 河南省高校科技创新团队(编号:2012IRTSTHN011); 郑州市科技领军人才(编号:0910SGYS3527)
  • 相关项目:益母草总碱治疗前列腺增生的分子机制研究
作者: 肖开|苗明三|
中文摘要:

目的:探讨中医药转化医学的研究模式及方法。方法:分析转化医学的提出背景和必然性,归纳总结转化医学的内涵特点、基本特征及研究方法,通过从理论基础、发展应用、研究思路、研究内容等方面进行对比,分析中医药体系与转化医学的关系。根据中医药特点提出中医药转化医学的理念,分析开展中医药转化医学的必要性和可行性,探讨中医药转化医学的研究方法、发展模式、前景意义和研究关键。结果:中医药与转化医学理论体系具有一致性,开展中医药转化医学研究可引导医学研究的实用性,是连接中医药基础研究与临床实践的桥梁;以临床实际需要为导向,采用实验室与临床研究的双向转化模式构建进行资源整合,以临床为中心的中医药新产品研究为中医药转化医学研究的突破口,明确药物机理,建立相应病症模型,进一步确定疾病的病因病机,并有效利用科研投入,使科研成果实现产品转化,以提高临床疗效为研究的唯一目的,是中医药转化医学研究的主要方法。结论:中医药转化医学是中医药未来发展的方向,中药新产品研究为中医药转化医学研究的突破口。

英文摘要:

Objective:To study the research model and methods of transformation of Traditional Chinese medicine into medical science.Methods:Analyze the proposed background and necessity of translation medicine.Discuss the connotation,basic characteristics and research methods of the translational medicine.Analyze the relationship between traditional Chinese medicine system and translational medicine through theoretical basis,development application,research ideas and content and so on.Put forward the conviction and necessity of translation medicine and discuss the methods,development patterns,significance and key point.Results:Traditional Chinese medicine and translational medicine theory system has uniformity.Develop transformation of traditional Chinese medicine into medical science may guide the practicality of medical research,as a connection of basic research and clinical practice.Use the two-way transformed mode of laboratory and clinical research for integration of resources and Chinese medicine new products research as breakthrough point for translation of traditional Chinese medicine.Make clear drug mechanism and set up corresponding disease model for further determination of the disease causes and mechanism.Utilize the input for scientific research in effect to transform the technological research findings into products in order to improve the clinical effect as the sole purpose and the main method for transformation of medical research.Conclusion:Transformation of traditional Chinese medicine into medical science is the future direction of the traditional Chinese medicine development.Chinese medicine new products research is the breakthrough point.

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