中文摘要：

用ELISA法测定了中药复方对热刺激小鼠脾脏IFN-γ和IL-4水平的影响。结果,高温对照组IFN-γ、IL-4和IL-4/IFN-γ上升,中药复方组IFN-γ从热刺激后第1天显著上升,第3天达高峰,第6天下降到常温对照组水平;IL-4在第1天显著下降,然后回升,第6天显著升高,第10天下降,接近常温对照组水平;IL-4/IFN-γ第1天显著降低,然后逐步回升。研究表明,热刺激会引起小鼠脾脏IFN-γ、IL-4水平的紊乱,中药复方有显著的调节作用,从而促进免疫功能的恢复。

英文摘要：

Splenic IFN-γ and IL-4 contents in mice under heat stimulation were detected with ELISA to evaluate the effects of Chinese herbal medicine on them. The results showed that all of IFN-γ and IL-4 contents and IL-4/IFN-γ ratio increased in high temperature control group （HTCG）; In Chinese herbal medicine group （CHMG）, IFN-γ content began to upgrade on the first day after heat stimulation, raised at peak on the 3^rd day, and then downgrade to the content of normal temperature control group （NTCG） on the 6^th day without significant difference; IL-4 content downgraded significantly on the first day, then upgraded gradually and dramatically on the 6^th day, and then downgraded to the content of NTCG; IL-4/IFN-γ ratio decreased significantly on the first day, and then increased gradually. In conclusion, the heat stimulation may cause the disorder of IFN-γ and IL-4 levels in mice spleen; Chinese herbal medicine have the significant effects of regulation on IFN-γ and IL-4 levels to improve and recover the immune function.