目的探讨高压氧(HBO)治疗对感音性耳聋患者铁缺乏等因素的影响。方法从1996年12月至2004年12月期间门诊和入院行HBO治疗感音性耳聋患者随机选择出253例,在HBO治疗前、HBO治疗1个和2个疗程后分别行血红蛋白(Hb)和血清铁(SI)含量的测定,并与2005年度健康体检中随机抽取与250例血液测定结果进行对照。结果HBO治疗2个疗程后轻度耳聋痊愈加显效例数显著高于中度耳聋(P〈0.05);HBO治疗1个疗程后与HBO治疗前以及HBO治疗2个疗程后与HBO治疗1个疗程后的Hb和SI含量比较差异有统计学意义(P〈0.05或P〈0.01);HBO治疗2个疗程后与正常对照组的Hb含量间差异无统计学意义(P〉0.05),而SI含量间的差异则有统计学意义(P〈0.05)。结论HBO对感音性耳聋患者的Hb和SI有调节作用。
Objective To evaluate the effect of hyperbaric oxygen(HBO) therapy on iron deficiency in patients with sensorineural deafness. Methods Two hundred and fifty three patients were randomly selected from outpatients and inpatients with sensorineural deafness and treated with HBO therapy from Dec. 1996 to Dec. 2004. Serum ferritin (SI) and hemoglobin (Hb) were measured before treatment and after one and two courses of treatment. Hb and SI were also measured in 250 peoples undergone healthy check-up in 2005. Results After two courses of HBO therapy,better curative effect was obviously shown in treating mild deafnes than in treating moderaie deafness. Statistically significant difference in Hb and SI was observed before treatment and after one course of treatment, also after one course of treatment and after two courses of treatment, respectively (P 〈 0. 05 ,P 〈 0. 01 ). There was no statistically significant difference in Hb between patients after two courses of treatment and healthy people ( P 〉 0.05 ), but there was a statistically significant difference in SI between them (P 〈 0. 05). Conclusion Hyperbaric oxygen therapy may adjust SI and Hb in patients with sensorineural deafness.