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A new guaiane-type sesquiterpene lactone from the Chinese liverwort Porella acutifolia subsp, tosana
  • ISSN号：2095-6975
  • 期刊名称：《中国天然药物：英文版》
  • 时间：0
  • 分类：R284.1[医药卫生—中药学;医药卫生—中医学]
  • 作者机构：[1]Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
  • 相关基金：This project was supported by the National Natural Science Foundation of China （No. 30925038）.
作者： LI Rui-Juan GUO Dong-Xiao LOU Hong-Xiang[1]
中文摘要：

试图学习中国地钱 Porella acutifolia subsp 的化学成分。tosana。混合物与列层析和他们的结构被孤立并且净化的方法根据 1D-NMR 和 2D-NMR 分析被决定。结果三混合物作为 guaian-3-en-2 被获得并且识别， 14-6， 12-diolide (1 ) ，(20R )-6-hydroxystigmasta-4, 22-dien-3-one (2 ) ，并且(20R )-3-hydroxystigmasta-5, 22-dien-7-one (3 ) 。结论化合物 1 是新 guaiane 类型 sesquiterpene 内酯。加重 2 和 3 被知道类固醇。

英文摘要：

AIM： To study the chemical constituents of the Chinese liverwort Porella acutifolia subsp, tosana. METHODS： The compounds were isolated and purified with column chromatography and their structures were determined on the basis of 1D- and 2D-NMR analysis. RESULTS： Three compounds were obtained and identified as guaian-3-en-2a, 14-6a, 12-diolide （1）, （20R）-6β- hydroxystigmasta-4, 22-dien-3-one （2）, and （20R）-3fl-hydroxystigmasta-5, 22-dien-7-one （3）. CONCLUSION： Compound 1 is a new guaiane-type sesquiterpene lactone. Compounds 2 and 3 are known steroids.

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期刊信息
  • 《中国天然药物：英文版》
  • 北大核心期刊（2008版）
  • 主管单位:中华人民共和国教育部
  • 主办单位:中国药科大学 中国药学会
  • 主编：吴晓明
  • 地址：南京童家巷24号中国药科大学2号信箱
  • 邮编：210009
  • 邮箱：cpucjnm@163.com
  • 电话：025-83271565 83271568
  • 国际标准刊号：ISSN：2095-6975
  • 国内统一刊号：ISSN：32-1845/R
  • 邮发代号:28-306
  • 获奖情况:
  • 国内外数据库收录:
  • 美国国际药学文摘,美国化学文摘（网络版）,波兰哥白尼索引,美国生物医学检索系统,美国科学引文索引（扩展库）,美国生物科学数据库,中国中国科技核心期刊,中国北大核心期刊（2008版）
  • 被引量:6564