一条简单、有效、 eco 友好的线路在水里经由醛, acetylacetone 和 thiol 的 multicomponent 反应为 -mercapto diketones 的合成被开发了。这方法论负担得起很多 -mercapto diketone 衍生物在对好收益中等。
A simple, efficient and eco-friendly route has been developed for the synthesis of fl-mercapto diketones via a multicomponent reaction of an aldehyde, acetylacetone and thiol in water. This methodology affords a number of β-mercapto diketone derivatives in moderate to good yields.