中文摘要：

去氢枞酸与SOCl2反应制得去氢枞酸酰氯（2）;芳磺酰氯与乙二胺经N-酰化反应制得N-芳磺酰基乙二胺（4a～4k）;在DMAP催化下,2分别与4a ～4k经N-酰化反应合成了11个新型的去氢枞酸基磺酰胺类化合物（5a～5k）,其结构经1H NMR,13C NMR,IR和ESI-MS表征.生物活性测试结果表明,在用药量为50μg·mL-1时,5a ～5k对黄瓜枯萎病菌、苹果轮纹病菌、番茄早疫病菌、花生褐斑病菌和小麦赤霉病菌有一定的抑菌活性,其中去氢枞酸基间甲基苯磺酰胺（5c）对番茄早疫病菌的杀菌活性最佳,抑制率为73.6％;在用药量为100 μg· mL-1时,大部分化合物对油菜的胚根生长有一定抑制作用,其中去氢枞酸基对甲氧基苯磺酰胺（5d）的抑菌活性最佳,抑菌率为57.1％.

英文摘要：

Dehydroabietic acid acyl chloride （2） was prepared by the reaction of dehydroabietic acid with thionyl chloride.N-aryl sulfonyl ethylenediamines（4a ～ 4k） was prepared by the N-acylation of aryl sulfonyl chloride with ethylenediamine.Eleven novel dehydroabietic acid-based sulfonamide compounds（5a ～ 5k） were synthesized by N-acylation reaction of 2 with 4a ～ 4k,respectively,using DMAP as the catalyst.The structures were characterized by 1H NMR,13C NMR,IR and ESIMS.The preliminary bioassay showed that 5a ～ 5k exhibited certain fungicidal activities against Fusarium oxysporum f.sp.cucumerinum,Physalospora piricola,Alternaria solani,Cercospora Rachidicola and Fusarium graminearum.Inhibition rate against Alternaria solani of dehydroabietic acid-based mmethyl-benzenesulfonamide（5c） was 73.6% at 50μg · mL-1.Most of 5a ～ 5k exhibited certain growth inhibition activities against rape root （Brassica campestris）,inhibition rate of dehydroabietic acid-based p-methoxyl-benzenesulfonamide（5d） was 57.1% at 100μg · mL-1.