中文摘要：

目的：依据受检者AMA-m^2检测结果分析判断AMA-m^2运用于原发性胆汁性肝硬化早期筛查的效果。方法：对我院体检中心体检的5400例研究对象进行血液检查,收集受检者清晨空腹静脉血,对分离出的血清进行AMA-m^2检测并分析受试者丙氨酸氨基转移酶、天门冬氨酸氨基转移酶等血清酶学检测数据。结果：5400例体检患者AMA-m^2检测中阳性患者有81例,阳性率为1.5%（81/5400）,其中男性阳性34例（1.14%）,女性阳性47例（1.94%）,男女之间的阳性率具有统计学意义（χ-2=5.819,P〈0.05）;45岁以下人群与46岁以上人群的AMA-m^2阳性率具有统计学意义（χ^2=10.473,P〈0.05）;AMA-m^2检测高浓度组的各项血清酶指标阳性率均明显高于低浓度组（P〈0.05）。结论：AMA-m2阳性是进行PBC早期筛查的重要依据。

英文摘要：

Objective： To determine the effect of AMA-m^2 on the early screening of primary biliary cirrhosis by AMA-m^2 test. Method： Blood tests were hcecked for 5400 subjects who came to our hospital physical examination center,was collected fasting venous blood,the serum was separated and examined with AMA-m-2,then alanine aminotransferase（ ALT）,aspartic acid aminotransferase detection data were analyzed. Result： The positive patients by AMA-m^2 test were 81 cases,the positive rate was 1.5%（ 81 / 5400）.34 males cases were positive（ 1.14%）,47 cases were positive for women（ 1. 94%）,the positive rate between men and women was statistical significant（ χ^2= 5.819,P〈0.05）; Positiue rate of people under the age of 45 and above the age of 46 had statistical significance（ χ^2= 10.473,P〈0.05）; The positive rate of serum enzyme indexes in high concentration group was significantly higher than that in low concentration group（ P〈0.05）. Conclusion： AMA-m^2 positive is an important basis index for early screening of PBC.