中文摘要：

探讨小花棘豆（Oxytropis glabraDC）对绵羊抗氧化能力的影响，揭示小花棘豆对绵羊的毒性作用机理。将16只绵羊随机分为4组。即对照组、试验I组、试验Ⅱ组和试验Ⅲ组．3个试验组分别按照每千克体重5、10、20g的剂量饲喂小花棘豆，至典型临床症状出现，通过采血检测绵羊红细胞和抗氧化指标的变化。结果显示，与正常对照相比，中毒绵羊血液红细胞数（RBC）、红细胞压积（HCT）、血红蛋白（HGB）、平均红细胞血红蛋白含量（MCH）、平均红细胞体积（MCV）、甘油三酯（TG）、总抗氧化能力（T-AOC）、超氧化物歧化酶（SOD）、谷胱甘肽过氧化物酶（GSH-Px）、过氧化氢酶（CAT）、黄嘌吟氧化酶（XOD）活性显著下降，红细胞分布宽度（RDW）、总胆固醇（TC）、丙二醛（MDA）、一氧化氮（NO）、一氧化氮合酶（NOS）、低密度脂蛋白（LDL-C）和极低密度脂蛋白（VLDL-C）含量均显著上升。结果表明。小花棘豆中毒可显著影响绵羊血液运氧和抗氧化能力．并影响绵羊的脂代谢。

英文摘要：

16 sheep were randomly and equally divided into 4 groups （the control group and experimental group Ⅰ,Ⅱ,Ⅲ ） to investigate the effect of Oxytropis glabra DC on anti-oxidative capacity, and reveal the toxicity mechanism of O. glabra DC. These experimental groups of sheep were fed daily with O. glabra DC at 5,10 or 20 g/（kg·d） until typical symptoms ob- served. During the test, blood routine items and biochemical parameters of each group were measured respectively. The results demonstrated that the activities of RBC, HCT,HGB,MCHC,MCV,TG,T-AOC,SOD,GSH-Px,CAT and XOD in the poisoned sheep were significantly dropped; the contents of RDW,TC,MDA,NO,NOS,LDL-C and VLDL-C in poisoned sheep were sig- nificantly higher than those of normal control group. The results showed that O. glabra DC has remarkable effects on transport oxygen, anti-oxidative capacity and lipid metabolism of sheep.