抗菌肽是一类生物体内产生的具有多种生物活性的小分子多肽,具有广谱的抑制细菌、真菌、病毒、寄生虫甚至肿瘤细胞、癌细胞的生物学活性。因其具有良好的抗菌活性和独特的杀菌机制,在养殖业中的应用越来越广泛。综述了天然抗菌肽的活性机制及其在畜(猪)、禽、反刍动物和水产养殖业中的应用进展,旨在为抗菌肽的功能开发及推广应用提供参考。
Antibacterial peptide is a kind of small molecule polypeptide,which has multiple biological activities and is produced in living organisms. It has broad-spectrum biological activity of killing bacteria,fungi,viruses,parasites,even tumor cell and cancer cell. Because of its good antibacterial activity and unique sterilization mechanism,it has been more and more widely used in the aquaculture industry. In this paper,the active mechanism of natural antibacterial peptide and its application in livestock( pig),poultry,ruminant and aquaculture breeding were described,which was aimed to provide the important reference for the function development and the application of future antibacterial peptide.