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中文摘要：
首次研究了一株南海红树内生真菌Microsphaeropsissp．的次级代谢产物。从该菌的培养液的乙酸乙酯相中分离获得8个二氢异香豆素单体化合物，运用现代波谱技术鉴定其结构分别为4-hydroxy-8-O-methylmellein（1），mellein（2），4-hydroxymellein（3），5-hydroxymellein（4），4-hydroxy-3，5-dimethylmellein（5），5-methylmellein（6），7-hydroxymellein（7），5-carboxymellein（8）。其中，化合物1为从自然界发现的新天然产物，化合物4，5，6，7，8为首次从海洋真菌Microsphaeropsissp．中分离得到的化合物。
英文摘要：
The secondary metabolites of the mangrove endophytic fungus Microsphaeropsis sp. from the South China Sea were first studied. Eight dihydroisocoumarin derivatives were isolated from the ethyl acetate extract of the fermentation. Their structures were identified by comprehensive spectroscopic methods as 4-hydroxy-8-O-methylmellein （ 1 ）, mellein （2）, 4-hydroxymellein （3）, 5-hydroxymellein （4）, 4- hydroxy-3, 5-dimethylmellein （5）, 5-methylmellein （6）, 7-hydroxymellein （7） and 5-carboxymellein （8）. Compound 1 was isolated as a natural compound for the first time and compounds 4, 5, 6, 7, 8 were first isolated from the fungus Microsphaeropsis sp.
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