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增殖诱导配体在自身免疫性疾病中的研究进展
  • ISSN号：1001-7097
  • 期刊名称：《中华肾脏病杂志》
  • 时间：0
  • 分类：R735.37[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构：[1]北京大学第一医院肾内科北京大学肾脏疾病研究所卫生部肾脏疾病重点实验室教育部慢性肾脏病防治重点实验室,100034
  • 相关基金：国家青年科学基金（81000297）;国家自然科学基金创新研究群体科学基金（81021004）
作者： 翟亚玲[1], 朱厉[1], 张宏[1]
关键词： 增殖诱导配体, 自身免疫性疾病, T淋巴细胞, LIGAND, 肿瘤坏死因子, 树突状细胞, APRIL, 免疫球蛋白
中文摘要：

增殖诱导配体（aproliferation—inducing ligand，APRIL）又名TNFSF13，是肿瘤坏死因子家族中的重要成员之一，主要表达于多种免疫细胞上，如树突状细胞、巨嗜细胞、单核细胞、T淋巴细胞等。APRIL通过与受体的结合，主要促进和参与淋巴细胞的增殖、分化、存活以及诱导免疫球蛋白的产生和发生类别转换等多种功能。

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期刊信息
  • 《中华肾脏病杂志》
  • 北大核心期刊（2011版）
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编：
  • 地址：广州市中山二路74号
  • 邮编：510089
  • 邮箱：cmaszb@mail.sysu.edu.cn
  • 电话：020-87331532
  • 国际标准刊号：ISSN：1001-7097
  • 国内统一刊号：ISSN：44-1217/R
  • 邮发代号:46-106
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2011版）,中国北大核心期刊（2014版）,中国北大核心期刊（2000版）
  • 被引量:26419