中文摘要：

瞄准改进诊断，磁性的回声成像(MRI ) 的联合和 X 光检查的敏感和精确性在探查在迫切需要的一个单身者计算了断层摄影术(CT ) 。这里，我们报导 polyacrylic 酸(泛美航空公司) 的发展与高纵的 relaxivity 作为新奇 MRI 和 CT 双模式的对比代理人(CA ) 盖住 GdF ₃ nanoplates (NP )(r ₁) 和大 X 光检查变细系数。一致 GdF ₃ 菱形的 NP 被控制反应条件并且介绍掺杂物制作。GdF ₃ NP 的平均尺寸是(10.6 吗？激光材料被表明。在另一方面，自从高温度，融化方法与

英文摘要：

Aiming at improving the sensitivity and accu- racy 9f diagnosis, the combination of magnetic resonance imaging （MRI） and X-ray computed tomography （CT） in a single probe is in urgent need. Here, we report the devel- opment of polyacrylic acid （PAA）-capped GdF3 nanoplates （NPs） as novel MRI and CT dual-mode contrast agents （CAs） with high longitudinal relaxivity （rl） and large X-ray attenuation coefficient. Uniform GdF3 rhombic NPs were fabricated by controlling reaction conditions and intro- ducing dopants. The average size of GdF3 NPs is （10.6 ：k 1.1） nm in long diagonal, （7.0 -t- 0.8） nm in short diagonal, and （4.2 -4- 1.2） nm in thickness. Ligand-exchange treat- ment was performed to render the NPs water-dispersible. The rl of PAA-capped GdF3 NPs （15.8 L/（mmol s）） is four times higher than that of clinically used Gd-DTPA. We suppose that the high r~ value originates from the con- struction of two-dimensional （2D） nanostructures, which endows nanocrystals with larger surface areas and longer rotational correlation time than those of sphere nanostruc- tures with the same volume. The CT contrast enhancement ability of PAA-capped GdF3 NPs was evaluated in com- parison with clinically used Iohexol. The above results suggest that the PAA-capped GdF3 NPs could serve as CAs for MRI and CT dual-mode imaging.