目的:评价婴幼儿社会认知发展筛查量表(中文版)筛查孤独症幼儿的诊断价值,制订合适的界值。方法:采用横断面研究。2066年10月到2007年5月,方便选取在广州市和佛山市3家医院进行儿童保健(N=564)或6家幼儿园上学(N=331)的正常婴幼儿为对象,收回有效问卷843份,用婴幼儿社会认知发展筛查量表中文版询问儿童养育者并现场观察儿童表现,制订9个年龄段婴幼儿全量表分数的95%参考值范围。2007年2~6月在中山大学第三附属医院选取来就诊的170例孤独症幼儿和进行儿童保健的391例正常幼儿进行调查,绘制3个年龄段(2.0岁~、2.5岁~和3.0岁-)婴幼儿的ROC曲线,以评价量表的诊断价值。结果:(1)843名正常婴幼儿量表得分随年龄增加而增加(F=643.83,P〈0.001)。9个年龄段婴幼儿全量表分数95%参考值范围分别为:10分~、19分~、25分-、28分~、29分~、32分~、52分~、54分~和62分-。(2)3个年龄段婴幼儿全量表分数的ROC曲线下面积分别为0.969、0.988和0.994(均P〈0.01);筛查能力最高时的全量表分数界值分别为52.5分、54.5分和63.5分。结论:婴幼儿社会认知发展筛查量表(中文版)筛查孤独症幼儿的能力较强,全量表分数的95%参考值范围确定的界值与ROC曲线确定的界值接近,可用全量表分数的95%参考值范围筛查孤独症幼儿。
Objective: To screen autism children by Chinese edition infant and early children social development screening test and to evaluate the diagnostic value. Methods: From October 2006 to May 2007, 843 normal children from 3 children health care clinics (N = 564 ) and 9 kindergartens ( N = 331) were selected and assessed with the Chinese Edition Infant and Early Children Social Development Screening Test. The 95% reference range was made. From February to June 2007, in the third affiliation hospital of Sun yet-san university, 170 children who were diagnosed as autism and 391 normal children were selected to draw ROC curve to evaluate the checklist's screening ability. Results: ( 1 ) The total scores of the scale were increased with the age of subjects ( F = 643.83, P 〈 0. 001 ) . ( 2 ) The areas below ROC curve of whole checklist corresponding three age period were 0. 969, 0. 988 and 0. 994. The scores of whole checklist were 52. 5, 54. 5 and 63. 5, when the screening ability was best. Conclusion: The diagnostic value of the checklist for autism children is so good that it is useful for clinical evaluation on the social cognitive development of young children between O. 5 - 3.5 years.