中文摘要：

单纯疱疹病毒-胸苷激酶（HSV-TK）目前已进行了恶性脑瘤、卵巢癌、前列腺癌等肿瘤的临床试验。结果表明，该基因疗法能够提高患者生活质量，延缓肿瘤生长、复发和转移，且无明显不良反应。

英文摘要：

Therapeutic efficacy and security of herpes simplex virus-thymidine kinase（HSV-TK） gene therapy has been evaluated by the treatment of malignant cerebroma, ovarian cancer, prostate cancer and etc. The results show that HSV-TK gene therapy can improve patients life quality, delay cancer growth, recurrence and metastasis, and it has no obvious side effects.