中文摘要：

麻醉药可导致老年大鼠出现术后早期甚至永久性的认知功能损伤,已基本得到证实。依托咪酯作为临床常用的麻醉药,对快速发育期大脑是否有影响是近来人们关注的问题,其机制的阐明对临床小儿合理用药具有指导意义。但其功能损害是否同时表现在空间认知功能和学习记忆等方面仍不清楚。现就麻醉药依托咪酯对快速发育期大脑影响的研究进展予以综述。

英文摘要：

It has been verified that the anaesthetics could cause early period or even permanently post operative cognitive dysfunction to the old rats.Etomidate as the clinical commonly used anaesthetics,its influence on the rapid developmental brain has raised people′s concern recently,and the clarification of mechanism has a guiding significance in clinic.But whether it′s functional lesion display in spatial cognitive performance,learning,memory or other aspects at the same time are not clear.Here is to make a review on the research progress of the etomidate′s effect on the rapid developing brain.