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腹腔镜联合药物治疗卵巢子宫内膜异位症的临床观察
  • ISSN号:0529-567X
  • 期刊名称:《中华妇产科杂志》
  • 时间:0
  • 分类:R711.11[医药卫生—妇产科学;医药卫生—临床医学]
  • 作者机构:[1]浙江省人民医院妇产科,浙江杭州310014
  • 相关基金:浙江省医药卫生科学研究基金项目(2006A06)
中文摘要:

目的观察腹腔镜手术联合孕三烯酮药物治疗卵巢子宫内膜异位症的临床效果及安全性评价。方法选择2009年1月~2010年12月在本院行腹腔镜手术治疗并术后诊断为卵巢子宫内膜异位症患者106例.随机分为治疗组及观察组,治疗组患者于术后第1次月经来潮第2天即给予疗程6个月的孕三烯酮口服,观察组术后不予任何药物治疗,所有患者均完成随访,末次随访日期至2011年12月,观察比较两组治疗效果及复发情况。结果两组患者腹腔镜手术均顺利完成,全部完成随访,治疗组用药不良反应轻微,均完成足疗程治疗,且治疗有效率及术后妊娠率明显高于对照组,复发率明显低于对照组,差异有统计学意义(P〈0.05)。结论卵巢子宫内膜异位症患者采用腹腔镜手术,术后联合孕三烯酮药物治疗,治疗效果显著,显著降低复发率,怀孕率得以提高,副反应小,值得临床推广应用。

英文摘要:

Objective To investigate the effects and safety of combinative treatment with laparoscopy and gestrinone on o- varian endometriosis. Methods A total of 106 cases diagnosed ovarian endometriosis were randomly divided into two groups,the treatment group and the observation group by laparoscopy during form January 2009 to December 2010.The pa- tients in the treatment group were given 2.5 mg of gestrinone for 6 months after operation. The cases in observation group had not taken any hormone. All patients were followed up until December 2011 to observe the therapeutic effect and re- currence. Results All the patients were successfully completed the laparoscopic surgery, the treatment group drug adverse reaction mild, all patients finished the total course, and treatment efficient and postoperative pregnancy rate was signifi- cantly higher than the observation group, the recurrence rate was significantly lower than the control group, the difference was statistically significant (P 〈 0.05). Conclusion Ovarian endometriosis patients using laparoscopic surgery, postoperative joint pregnant three ketene drug treatment, the treatment effect is remarkable,and can remarkablely decrease the recurrence rate, the pregnancy rate can improved, and have small side effects, worth of clinical application.

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期刊信息
  • 《中华妇产科杂志》
  • 中国科技核心期刊
  • 主管单位:中国科协
  • 主办单位:中华医学会
  • 主编:
  • 地址:北京市东四西大街42号
  • 邮编:100710
  • 邮箱:cjog@cma.org.cn
  • 电话:010-85158215
  • 国际标准刊号:ISSN:0529-567X
  • 国内统一刊号:ISSN:11-2141/R
  • 邮发代号:2-63
  • 获奖情况:
  • 获国家科委优秀期刊二等奖,获中国科协优秀期刊二等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国生物医学检索系统,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版),中国北大核心期刊(2000版)
  • 被引量:76322