中文摘要：

客观房间和医药 biomaterial 的相互作用是重要因素之一影响医药 biomaterial 的临床的申请。这研究是调查三根缝术线怎么在 vitro 影响增长和肺腺癌房间 A549 的房间周期。，三缝术衬里的方法分别地 72 个小时与肺腺癌房间 A549 被栽培，我们由 MTT 方法检测了每个组的吸收以便反映肺腺癌房间 A549 的增长，并且也由流动 cytometry 检验了 G1 时期房间的百分比和每个组的 S 时期房间。缝术线不同的结果在增长和肺腺癌房间 A549 的房间周期上有不同效果(P < 0.05 ) 。吸收剂缝术线的效果在增长和肺腺癌房间 A549 的房间周期上是最强壮的，索 serica chirurgicalis 的效果是中等的，并且幻灯片电线的效果是差的。每根缝术线的不同长度在增长和肺腺癌房间 A549 的房间周期上有不同效果(P < 0.05 ) 。结论三缝术线材料在增长和肺腺癌房间 A549 的房间周期上有不同效果，与剂量效果关系。

英文摘要：

Objective： The interaction of cell and medical biomaterial is one of the significant factors to affect clinical application of medical biomaterial. This research is to investigate three of suture lines how to affect the proliferation and cell cycle of lung adenocarcinoma cell A549 in vitro. Methods： Three of suture lines were respectively cultivated with lung adenocarcinoma cell A549, after of 72 hours, we detected absorptions of each group by MTT method in order to reflect the proliferation of lung adenocarcinoma cell A549, and also examined percentage of G1 period cells and S period cells of each group by flow cytometry. Results： Different of suture lines had different effects on the proliferation and cell cycle of lung adenocarcinoma cell A549 （P 〈 0.05）. The effect of absorbent suture line was the strongest on the proliferation and cell cycle of lung arlenecarcinoma cell A549, the effect of chorda serica chirurgicalis was medium, and the effect of slide wire was poor. Different length of each suture line had different effects on the proliferation and cell cycle of lung adenocarcinoma cell A549 （P 〈 0.05）, Conclusion： Three of suture line materials have different effects on the proliferation and cell cycle of lung adenocarcinoma cell A549, with dose-effect relationship.