肺癌患者不但自身细胞免疫功能低下,而且肺癌组织可以产生大量免疫抑制因子(TDSF)促成肺癌患者免疫功能障碍。肺癌患者在接受手术、化疗、放疗后免疫功能进一步损伤。医用生物材料植入后导致细菌生物膜相对更易出现,细菌生物膜的形成是导致生物材料植入后感染难治性的主要根源。文章就肺癌患者以生物材料为中心细菌感染的研究进展及防治进行综述。
Lung cancer patients have decreased cellular immune function and tissues can produce a large number of the immunosuppressive factors(TDSF) resulting in immune dysfunction. The immune function of lung cancer patients will further injury after surgery, chemotherapy and radiotherapy. Biological materials plant led to the emergence of bacterial biofilms which is the key reason for refractoriness of biomaterials related infections more easily. The research on progress in biomaterials related infections of lung cancer patients is reviewed in this paper.