中文摘要：

为了降低含铜宫内节育器（Cu-IUD）引起的出血、疼痛和盆腔炎等副作用，本研究制备了新型的IUD用铜／氧化锌／低密度聚乙烯（Cu／ZnO／LDPE）纳米复合材料。并对复合材料的Cu^2＋和Zn^2＋释放行为，以及复合材料的表面特征进行了分析。结果表明，在释放初期阶段，纳米铜和纳米氧化锌含量的增加会抑制对方离子的释放；但在释放后期，则对对方离子的释放不产生显著影响。浸泡后的复合材料表面有大量沉积物，沉积物主要由CuO、Cu2（OH）3Cl、CaNa（H2PO4）3、CaZn（H2PO4）3和Zn4CO3（OH）6·H2O等成分组成。

英文摘要：

To decrease the side effects associated with copper-bearing intrauterine device （Cu-IUD） such as irregular bleeding, pain and pelvic inflammatory disease, copper/zinc oxide/low-density polyethylene （Cu/ZnO/LDPE） nanocomposites were prepared for the novel material used for IUD. The profile of Cu^2＋ and Zn^2＋ release was investigated by absorbance measurements. Cu^2＋ release rate is inhibited in the initial stage but is not affected greatly in the later stage by increasing the mass fraction of zinc oxide nanoparticles. The similar result is obtained for Zn^2＋ release with the increase of copper nanoparticles, which can be explained that copper and zinc oxide nanoparticles can suppressed the dissolution each other, but provide the pathways for ions release mutually at the same time. The surface characteristic of the nanocomposite is examined by using SEM, EDX and XRD. The unwanted deposits observed on the nanocomposite are consisted of CuO、Cu2（OH）3Cl、CaNa（H2PO4）3、CaZn（H2PO4）3 and Zn4CO3（OH）6·H2O.