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不同手法针刺足三里的脊髓背根神经电信号聚类分析

ISSN号：0493-2137
期刊名称：天津大学学报
时间：2011
页码：412-416
分类：TP391[自动化与计算机技术—计算机应用技术;自动化与计算机技术—计算机科学与技术] TH772[机械工程—仪器科学与技术;机械工程—精密仪器及机械]
作者机构：[1]School of Electrical and Automation Engineering, Tianjin University, Tianjin 300072, China, [2]School of Automation and Electrical Engineering, Tianjin University of Technology and Education, Tianjin 300222, China
相关基金：Project supported by the Key Program of the National Natural Science Foundation of China （Grant No. 50537030）, the National Natural Science Foundation of China （Grant No. 61072012）, and the Young Scientists Fand of the National Natural Science Foundation of China （Grant Nos. 50907044, 61104032, and 60901035）.
相关项目：基于放电起始动力学理论的针刺神经编码机制研究

关键词：脑电图, 互信息, 针灸, 大脑皮层, 特征, 电子信息, 临床应用, 信息交流, electroencephalograph, acupuncture, mutual information Lempel Ziv complexitymethod

中文摘要：

As a convenient approach to the characterization of cerebral cortex electrical information,electroencephalograph (EEG) has potential clinical application in monitoring the acupuncture effects.In this paper,a method composed of the mutual information method and Lempel-Ziv complexity method (MILZC) is proposed to investigate the effects of acupuncture on the complexity of information exchanges between different brain regions based on EEGs.In the experiments,eight subjects are manually acupunctured at ’Zusanli’ acupuncture point (ST-36) with different frequencies (i.e.,50,100,150,and 200 times/min) and the EEGs are recorded simultaneously.First,MILZC values are compared in general.Then average brain connections are used to quantify the effectiveness of acupuncture under the above four frequencies.Finally,significance index P values are used to study the spatiality of the acupuncture effect on the brain.Three main findings are obtained:(i) MILZC values increase during the acupuncture;(ii) manual acupunctures (MAs) with 100 times/min and 150 times/min are more effective than with 50 times/min and 200 times/min;(iii) contralateral hemisphere activation is more prominent than ipsilateral hemisphere’s.All these findings suggest that acupuncture contributes to the increase of brain information exchange complexity and the MILZC method can successfully describe these changes.

英文摘要：

As a convenient approach to the characterization of cerebral cortex electrical information, electroencephalograph （EEG） has potential clinical application in monitoring the acupuncture effects. In this paper, a method composed of the mutual information method and Lempel-Ziv complexity method （MILZC） is proposed to investigate the effects of acupuncture on the complexity of information exchanges between different brain regions based on EEGs. In the experiments, eight subjects are manually acupunctured at ＇Zusanli＇ acupuncture point （ST-36） with different frequencies （i.e., 50, 100, 150, and 200 times/min） and the EEGs are recorded simultaneously. First, MILZC values are compared in general. Then average brain connections are used to quantify the effectiveness of acupuncture under the above four frequencies. Finally, significance index P values are used to study the spatiality of the acupuncture effect on the brain. Three main findings are obtained：（i） MILZC values increase during the acupuncture; （ii） manual acupunctures （MAs） with 100 times/rain and 150 times/min are more effective than with 50 times/min and 200 times/rain; （iii） contralateral hemisphere activation is more prominent than ipsilateral hemisphere＇s. All these findings suggest that acupuncture contributes to the increase of brain information exchange complexity and the MILZC method can successfully describe these changes.

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