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Parietal cortex contributions to information granules following memory consolidation
  • ISSN号:1001-6538
  • 期刊名称:科学通报(英文版)
  • 时间:0
  • 页码:2671-2676
  • 语言:中文
  • 分类:TP311.13[自动化与计算机技术—计算机软件与理论;自动化与计算机技术—计算机科学与技术] Q426[生物学—神经生物学;生物学—生理学]
  • 作者机构:[1]Learning & Cognition Laboratory, International WIC Institute, Beijing University of Technology, Beijing 100022, China, [2]Harbin Normal University, Harbin 150301, China, [3]Department of Life Science and Informatics, Maebashi Institute of Technology, Maebashi, Japan, [4]Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • 相关基金:This work was supported by the National Natural Science Foundation of China (60673015, 60775039 and 08BTQ024), and the Grant-in-aid for Scientific Research (18300053)from the Japanese Ministry of Education, Culture, Sports, Science and Technology. The authors thank Erik, Tu HongQin, Ding LingLing and an anonymous reviewer for their informative commentary on a previous version of this article.
  • 相关项目:人脑归纳推理过程的动态时空特性研究
中文摘要:

以前的研究在伴随记忆形成和巩固的服的外皮活动集中了于变化。尽管在记忆检索的顶骨外皮的角色很好被建立,为数学规则的顶骨外皮记忆巩固怎么与存储信息的颗粒度有关,很好没被理解(即,详细或精确的度) 。在与记忆巩固联系的顶骨外皮活动的变化用 Ebbinghaus 范例和功能的磁性的回声成像(fMRI ) 被分析。在 1 个星期的功课上,参加者学习了包含印射包含低颗粒度或高颗粒度的信息的规则的刺激反应的布尔算术任务。FMRI 图象在白天 1 上被收集(即,低颗粒度的状况) 并且白天 7 (即,高颗粒度的状况) 。现在的数据与实践建议了那,存储信息被变换从一对一种高颗粒度的形式低颗粒度。由后面的统治学习,巩固的过程将包含规则表示颗粒度的增加的度,这被假设。为这个过程的证据在顶骨外皮活动被反映。这发现与在顶骨外皮的记忆的重建为存储器巩固被要求的假设一致,并且结果建议信息小粒在存储器巩固期间被形成。现在的结果能增加在记忆巩固和信息颗粒度之间的关系的理解。

英文摘要:

Previous studies have focused on changes in cerebral cortex activity accompanying memory formation and consolidation. Although the role of the parietal cortex in memory retrieval is well established, it is not well understood how parietal cortex memory consolidation for mathematical rules is related to granularity of stored information (i.e., degree of detail or precision). Changes in parietal cortex activity associated with memory consolidation were analyzed using the Ebbinghaus paradigm and functional magnetic resonance imaging (fMRI). Over the course of 1 week, participants learned Boolean arithmetic tasks involving stimulus-response mapping rules containing either lowor high-granularity information. FMRI images were collected on day 1 (i.e., low-granularity condition) and day 7 (i.e., high-granularity condition). The present data suggested that with practice, stored in- formation was converted from a low-granularity to a high-granularity form. By following rule learning, it was hypothesized that the process of consolidation would involve an increased degree of rule representation granularity. Evidence for this process was reflected in parietal cortex activity. This finding was consistent with the hypothesis that mnemonic reconstruction in the parietal cortex is required for memory consolidation, and results suggested that information granules are formed during memory consolidation. The present results could increase the understanding of the relationship between memory consolidation and information granularity.

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