中文摘要：

目的：观察路路通注射液改善烧伤微循环障碍的作用。方法：88例符合轻度烧伤诊断标准的患者被随机分为两组。治疗组伤后1d开始静脉使用路路通注射液500mg，加入到质量分数为5％的葡萄糖溶液中，每日1次，14d为1个疗程；对照组静脉仅使用5％的葡葡糖溶液；两组患者因轻度烧伤无休克均未进行补液疗法，均以克林霉素0．6g抗感染。观察烧伤3、7和14d治疗组与对照组血管襻形态、襻周状态、血液流变学指标变化及凝血功能状态改变，同时观察药物的不良反应。结果：与对照组比较，治疗组微血管动脉扩张明显，血流加快，末梢循环的流态积分值明显降低，襻周状态明显改变，总积分值下降较快，红细胞聚集指数及白细胞黏着数无明显改变，凝血功能变化不明显。2例患者出现头晕。结论：路路通注射液能改善烧伤患者的微循环，无明显的不良反应。

英文摘要：

Objective： To observe the effects of Lulutong injection on microcrculation disturbance after burns. Methods： Eighty-eight patients with mild burn were randomly divided into two groups. From the first day after burn, the treatment group received 500mg Lulutong injection intravenously injected in 5% glucose, once a day for 14 days as a therapeutic course. The control group was treated with 5% glucose. No large amount of solution was infused because the burned patients were mild and no shock was found. Both groups were received anti-infection treatment using 0.6 g of clindamycin. The morphology of nail-fold microcirculation, the state around the nail fold microcirculation, hemorrheological parameters, changes in coagulation function 3, 7 and 14 days after burn and the side effects of drugs were observed. Resuits： Compared to the control group, in the treatment group, the arterioles dilated more markedly, the blood flow of micro-vessels became faster, the flowing score of nail-fold microcirculation decreased obviously, the state around the nail-fold microcirculation changed significantly, the total score declined faster, but no obvious changes were found in erythrocyte aggregation index, the number of leukocyte adhesion and coagulation function. There were 2 cases with dizziness. Conclusion： Lulutong injection may improve the microcirculation in patients with burn, and has little side effect.