中文摘要：

分别以三种芳胺和三种杂环胺合成六种盐酸盐,再与双氰胺反应合成六种双胍类盐酸盐,最后将姜黄素与六种双胍类衍生物进行反应,最终合成六种姜黄素双胍类衍生物。通过IR、1H NMR、13C NMR对其结构进行了表征,初步证明合成了目标产物;利用循环伏安方法对目标产物进行了电化学性质研究,考察了在酸性条件下不同扫描速率下目标产物氧化还原峰位置的变化,表明反应过程受电极/溶液界面间的吸附控制。对目标产物进行了金黄色葡糖糖球菌的抑菌活性的研究,结果表明目标产物均有很好的抑菌效果。

英文摘要：

Curcumin and biguanides derivatives were synthesized with three kinds of aromatic amines,three kinds of heterocyclic amines,dicyandiamide and curcumin,using the organic synthesis method.The six kinds of curcumin and biguanides derivatives were confirmed by IR,1H NMR and 13 C NMR.The CV was used to investigate the electrochemical property of the six kinds of curcumin and biguanides derivatives.The results showed that the reaction process was affected by adsorption control through different scan rate in the electrode/solution interface under acidic condition.The six kinds of curcumin and biguanides derivatives were explored with Staphylococcus aureus,the results showed that the inhibition effect of the curcumin and biguanides derivatives were well.